The West Indies Academy levelled the series with an emphatic seven wicket win over Emerging Ireland in a match that was over before the lunch interval.
Once again the Irish top order batting failed, but unlike Friday, there was no late order revival to bail them out.
Scott Macbeth top scored with 29, while skipper Stephen Doheny hit 27, and Friday centurion Murray Commins made 16.
The hosts bowlers kept the pressure on throughout with wickets for Ashmead Nedd 3-12, Joshua Bishop 3-20, McKenny Clarke 2-20, and Nyeem Young 2-21.
To be able to defend a meagre 103 the Irish would have to make early inroads, but although Fionn Hand (2-29) and Matthew Foster (1-19) did have some success, the result was never in doubt.
Jordan Johnson cleared the ropes three times and hit four boundaries in a rapid unbeaten 40 from just 21 balls, adding 67 with Teddy Bishop (32*) as the target was reached in the 16th over.
The teams will meet in the third and deciding one-day game on Tuesday, before the attention switches to the red-ball format.