Bready made it 9 wins from 9 with a 14-run win over Eglinton, while there were victories too for Fox Lodge and Coleraine.
The champions were presented with the Premiership title before the game, but it looked as they could be in trouble after posting a modest 98 for 8 - Cody Wallace making 21 not out and Jenni Jackson taking three wickets for the villagers.
Eglinton threatened briefly as Zara Craig made 26, but four wickets for Wallace and two apiece for Charley Scott and Alana Dalzell sealed a narrow 14-run verdict.
Fox Lodge sealed second place with a 91-run win over Strabane after posting 183 for 4.
Mollie Devine top scored with 76 from 46 balls (10 fours, 2 sixes), sahring a second wicket stand of 140 in 14 overs with Lucy Neely, who hit 4 sixes and 4 fours in her 59-ball 67.
Chloe Deans (2-29) was the pick of the bowlers, and Emma Doherty's unbeaten 38 the highlight of their 92 for 6 - two wickets apiece for Mollie Devine and Kara Bates.
Coleraine stay in third place after an 8 wickets win over Bonds Glen.
Skipper Lucy Thompson made 37 as the Bee Gees scored 110 for 6 - three wickets for Connie Block (3-16).
Hannah Skinner (42) and Rachel Johnson (22) helped the Bannsiders chase it down in the penultimate over.
NW WOMEN'S PREMIERSHIP
At Magheramason, Bready beat Eglinton by 14 runs
Bready 98/8 (20 overs;Cody Wallace 21*; Jenny Jackson 3-17)
Eglinton 84 (19.4 overs; Zara Craig 26; Cody Wallace 4-19, Charley Scott 2-7, Alana Dalzell 2-12)
At Strabane Academy, Fox Lodge beat Strabane by 91 runs
Fox Lodge 183/4 (20 overs; Mollie Devine 76, Lucy Neely 67; Chloe Deans 2-28)
Strabane 92/6 (20 overs; Emma Doherty 38*; Mollie Devine 2/3, Kara Bates 2-19)
At Sandel Lodge, Coleraine beat Bonds Glen by 8 wickets
Bonds Glen 110/6 (20 overs; Lucy Thompson 37; Connie Block 3-16)
Coleraine 111/2 (18.5 overs; Hannah Skinner 42, Rachel Johnston 22, Kenya McCartney 19*)